TARGETED THERAPY AS A POTENTIAL DE-ESCALATION STRATEGY IN LOCALLY ADVANCED HPV-ASSOCIATED OROPHARYNGEAL CANCER: A LITERATURE REVIEW

Targeted Therapy as a Potential De-Escalation Strategy in Locally Advanced HPV-Associated Oropharyngeal Cancer: A Literature Review

The treatment landscape of locally advanced HPV-oropharyngeal squamous cell carcinoma (OPSCC) is undergoing transformation.This is because the high cures rates observed in OPSCC are paired with severe treatment-related, long-term toxicities.These significant adverse effects have led some to conclude that the current standard of care is over-treatin

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Self-Supervised Learning-Based Time Series Classification via Hierarchical Sparse Convolutional Masked-Autoencoder

In recent years, the use of time series analysis has become widespread, prompting researchers to explore methods to improve classification.Time series self-supervised learning has emerged as a significant area of study, aiming to uncover patterns in unlabeled data for richer information.Contrastive self-supervised TRAINING AIDS learning, particular

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Knoetschkesuchus langenbergensis gen. nov. sp. nov., a new atoposaurid crocodyliform from the Upper Jurassic Langenberg Quarry (Lower Saxony, northwestern Germany), and its relationships to Theriosuchus.

We report a new, small-sized atoposaurid crocodyliform from the Upper Jurassic of Langenberg, Northeastern Germany.Atoposaurids are small-sized Mesozoic crocodyliforms of mainly European distribution, which are considered to be phylogenetically close to the origin of Eusuchia.Knoetschkesuchus langenbergensis gen.nov.sp.nov.is represented by two wel

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